A novel neoantigen discovery approach based on chromatin high order conformation.

Yi ShiMingxuan ZhangLuming MengXianbin SuXueying ShangZehua GuoQingjiao LiMengna LinXin ZouQing LuoYaoliang YuYanting WuLintai DaTom Weidong CaiGuang HeZe-Guang Han

Published in: BMC medical genomics (2020)

We believe that the 3D genome information will help to increase the precision of neoantigen prioritization and discovery and eventually benefit precision and personalized medicine in cancer immunotherapy.

Keyphrases

small molecule
high throughput
genome wide
gene expression
dna damage
transcription factor
molecular dynamics simulations
health information
dna methylation
healthcare