Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts.

Juliana Mozer ScianiBianca ZycharLuis Roberto GonçalvesRenata GiorgiThiago NogueiraDaniel Carvalho Pimenta

Published in: The journal of venomous animals and toxins including tropical diseases (2017)

One isolated molecule from the spine extract of E. lucunter is able to elicit inflammation and hypernociception in animal models, which is in agreement with the effects observed in sea urchin accidents.

Keyphrases

oxidative stress
neuropathic pain
spinal cord