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Cardiovascular adverse events associated with immune checkpoint inhibitors: A retrospective multicenter cohort study.

Yi ZhengZiliang ChenWenhua SongYu XuZhiqiang ZhaoYihong SunYuanyuan WangXuhong GengJun ZhaoXiaowei ZhangYanmin XuJeffrey Shi Kai ChanGary TseGuangping LiLili HongTong Liu
Published in: Cancer medicine (2024)
Elevated CK-MB after ICI treatment is the independent risk factor for the incidence of ICI-associated myocarditis, and elevated cTnI and NLR after ICI treatment are the independent risk factors for the development of ICI-associated severe myocarditis. CK-MB, cTnI, and NLR demonstrated a promising predictive utility for the identification of ICI-associated myocarditis and severe myocarditis.
Keyphrases
  • early onset
  • risk factors
  • protein kinase
  • combination therapy