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A phase II basket trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors (DART SWOG 1609 Cohort 47) in patients with gestational trophoblastic neoplasia.

Sandip Pravin PatelMegan K D OthusYoung Kwang ChaeMichael J DennisSarah GordonDavid G MutchWolfram E SamlowskiWilliam R RobinsonElad SharonChristopher RyanGabby LopezMelissa PletsCharles David BlankeRazelle Kurzrock
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Ipilimumab plus nivolumab demonstrated efficacy in chemotherapy-refractory GTN, an ultra-rare cancer affecting young women. Three out of four patients achieved ongoing objective responses with a reasonable safety profile at 6-11+ months.
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