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Transgenerational epigenetic information through the sperm: Sperm cells not just merely supply half of the genome for new life; they also seem to transmit additional information via epigenetic modifications.

Noriko OsumiMisako Tatehana
Published in: EMBO reports (2021)
The biological cause for the increase in Autism Spectrum Disorder may be fathers' older age and the epigenetic marks it leaves on sperm cells.
Keyphrases
  • induced apoptosis
  • dna methylation
  • autism spectrum disorder
  • gene expression
  • cell cycle arrest
  • endoplasmic reticulum stress
  • genome wide
  • cell death
  • attention deficit hyperactivity disorder
  • signaling pathway