Feasibility of Skin Water Content Imaging Using CMOS Sensors.

Pressure injuries (PI) result from pressure-induced damage to the skin and underlying tissues. Currently, Stage I PI are detected using visual skin assessments. However, this visual method is unable to detect skin color changes in persons with darkly pigmented skin, which results in a higher Stage II-IV PI incidence and PI-associated mortality in persons with a darker complexion. Thus, a more objective method of early-stage PI detection is of great importance. Optical spectroscopy is a promising modality for the noncontact diagnosis and monitoring of skin water content, capable of detecting edema and Stage I PI. The scope of the current study is to assess the feasibility of imaging the water content of the skin using Si-based sensors. We have considered two primary cases: the elevated bulk water content (edema) and localized water pool (e.g., blood vessels). These two cases were analyzed using analytical models. We found that detecting the watercontent contrast associated with edema in tissues is within the reach of Si-based sensors. However, although the effect is expected to be detectable even with consumer-grade cameras, with the current state of technologies, their use in real-world conditions faces numerous technical challenges, mainly due to the narrow dynamic range.