Impact of low-dose acetylsalicylic acid on pregnancy outcome in systemic lupus erythematosus: results from a multicentre study.

Chiara TaniDina ZucchiIsabell HaaseMaria GerosaMaddalena LarosaLorenzo CavagnaAlessandra BortoluzziFrancesca CrisafulliJohanna MuckeFrancesca A L StriginiLaura BagliettoMarco ForniliFrancesca MonacciElena ElefanteRoberta ErraElisa BellisMelissa PadovanLaura AndreoliLavinia Agra ColettoGiovanni ZanframundoMarcello GovoniLuca IaccarinoAngela TincaniAndrea DoriaRebecca Fischer-BetzMarta Mosca

Published in: Lupus science & medicine (2022)

In pregnant patients with SLE without renal involvement and were aPL-negative, there is a low risk of severe obstetric complications, such as early pre-eclampsia. LDASA treatment does not provide a statistically significant advantage over these complications. However, a careful individual risk-benefit balance is warranted.

Keyphrases

low dose
pregnant women
systemic lupus erythematosus
risk factors
high dose
preterm birth
early onset
disease activity
pregnancy outcomes
rheumatoid arthritis