Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.
Carmen De CaroRoberto RussoCarmen AvaglianoClaudia CristianoAntonio CalignanoAndrea AraminiGianluca BianchiniMarcello AllegrettiLaura BrandoliniPublished in: British journal of pharmacology (2018)
Our findings, in agreement with previous literature, encourage further studies for a better comprehension of the therapeutic potential of TRPM8 blockers as novel agents for pain management.
Keyphrases
- pain management
- chronic pain
- liver failure
- systematic review
- respiratory failure
- angiotensin converting enzyme
- oxidative stress
- drug induced
- aortic dissection
- case control
- cerebral ischemia
- anti inflammatory
- human health
- binding protein
- hepatitis b virus
- extracorporeal membrane oxygenation
- climate change
- angiotensin ii
- mechanical ventilation
- subarachnoid hemorrhage