CD39 and LDHA affects the prognostic role of NLR in metastatic melanoma patients treated with immunotherapy.
Domenico MallardoMario FordelloneAndrew WhiteMargaret OttavianoFrancesca SparanoMichael D BaileyArianna Bianca FacchiniSufey OngPiera MaiolinoCorrado CaracòSarah ChurchErnesta CavalcantiSarah WarrenAlfredo BudillonAlessandra CesanoEster SimeonePaolo ChiodiniPaolo Antonio AsciertoPublished in: Journal of translational medicine (2023)
These results suggest that increasing NLR is associated with an increased neutrophil population, with polarization to the N2 phenotype, and this process may be the basis for the negatively prognostic role of NLR.
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