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Liraglutide Attenuates Myocardial Fibrosis via Inhibition of AT1R-Mediated ROS Production in Hypertensive Mice.

Peng ChenFen YangWenya WangXiao LiDongling LiuYongxi ZhangGuotian YinFenghua LvZhikun GuoJawahar Lal MehtaXianwei Wang
Published in: Journal of cardiovascular pharmacology and therapeutics (2020)
Liraglutide reduces myocardial fibrosis in the hypertensive mice, which appears to be dependent on at least in part inhibition of ROS production.
Keyphrases
  • blood pressure
  • high fat diet induced
  • left ventricular
  • cell death
  • dna damage
  • reactive oxygen species
  • heart failure
  • liver fibrosis
  • adipose tissue
  • metabolic syndrome
  • skeletal muscle
  • atrial fibrillation