Risk factors and immunomodulators use in steroid-refractory checkpoint inhibitor pneumonitis.

Yanlin LiXiaohui JiaYajuan ZhangYonghao DuYuzhu ChangYuan ShenZiyang MaoMengjie LiuHong SunHui Guo

Published in: Journal for immunotherapy of cancer (2023)

Grade 3-4 and higher peripheral blood ANC at diagnosis are associated with higher risk of steroid-refractory CIP. The use of additional IMs improves the outcome of grade 3-4 steroid-refractory CIP. These results can offer new insights to the decision-making of CIP management.

Keyphrases

peripheral blood
risk factors
decision making
dna damage
cell cycle
cell proliferation
systemic sclerosis
oxidative stress
interstitial lung disease
rheumatoid arthritis