Epicardial adipose tissue thickness assessed by CT is a marker of atrial fibrillation in stroke patients.
Fabian EdsenPardes HabibOliver MatzOmid NikoubashmanMartin WiesmannMichael FrickNikolaus MarxJörg Bernhard SchulzArno ReichJoão PinhoPublished in: Annals of clinical and translational neurology (2022)
Epicardial adipose tissue is involved in the pathophysiology of atrial fibrillation (AF). This study aimed to analyze its relevance as a stroke etiology marker. A retrospective study of acute ischemic stroke patients with large vessel occlusion was conducted, periatrial epicardial adipose tissue thickness (pEATT) on admission computed tomography angiography was measured. One hundred and twenty-one patients with AF-related stroke and 94 patients with noncardioembolic stroke were included. Patients with AF-related stroke had increased pEATT. CT-measured left-sided pEATT was an independent predictor of AF-related stroke (adjusted odds ratio per 1 mm increase = 1.27, 95% CI = 1.05-1.53, p = 0.012). pEATT is an independent marker of AF-related stroke.
Keyphrases
- atrial fibrillation
- adipose tissue
- oral anticoagulants
- catheter ablation
- left atrial
- left atrial appendage
- direct oral anticoagulants
- heart failure
- acute ischemic stroke
- percutaneous coronary intervention
- insulin resistance
- computed tomography
- image quality
- emergency department
- magnetic resonance imaging
- acute coronary syndrome
- contrast enhanced
- venous thromboembolism
- blood brain barrier
- mitral valve
- pet ct
- left ventricular