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Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals.

Masahiro TakahashiKazuyoshi HosomichiTetsutaro YamaguchiKeisuke YanoTakahiro FunatsuMohamed AdelShugo HagaKoutaro MakiAtsushi Tajima
Published in: Human genome variation (2017)
A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.
Keyphrases
  • cone beam computed tomography
  • genome wide
  • endothelial cells
  • risk assessment
  • intellectual disability
  • induced pluripotent stem cells
  • dna methylation
  • transcription factor