Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma.

Carlo FurlanJerry PoleselLuigi BarzanGiovanni FranchinSandro SulfaroSalvatore RomeoFrancesca ColizziAurora RizzoVittorio BaggioVittorio GiacomarraAngelo Paolo Dei TosPaolo Boscolo-RizzoEmanuela VaccherRiccardo DolcettiLuca SigalottiElisabetta Fratta

Published in: Clinical epigenetics (2017)

LINE-1 hypomethylation is associated with higher risk of early relapse in stage III-IVB OPSCC. Further validation in a prospective study is needed for its application in daily clinical practice.

Keyphrases

squamous cell carcinoma
clinical practice
physical activity
free survival
locally advanced