Respiratory characteristics and related intraoperative ventilatory management for patients with COVID-19 pneumonia.
Hiroko AoyamaKanji UchidaPublished in: Journal of anesthesia (2020)
A substantial proportion of patients with coronavirus disease 19 (COVID-19) develop severe respiratory failure. Although the exact pathophysiology of severe COVID-19 pneumonia remains unknown and the characteristics of these patients are heterogeneous, the acute respiratory failure often fulfills criteria for acute respiratory distress syndrome (ARDS) and the clinical characteristics are also consistent with what is previously known about ARDS. Cohort studies also report distinctively high association between perioperative COVID-19 and postoperative mortality. In this special article, we review several publications on the pathophysiology of COVID-19, and discuss intraoperative ventilatory management for patients with COVID-19 based on the respiratory characteristics of COVID-19 pneumonia in light of the ongoing controversy of clinical phenotypes.
Keyphrases
- respiratory failure
- coronavirus disease
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- mechanical ventilation
- sars cov
- respiratory syndrome coronavirus
- intensive care unit
- patients undergoing
- end stage renal disease
- chronic kidney disease
- early onset
- newly diagnosed
- coronary artery disease
- risk factors
- hepatitis b virus
- cardiac surgery
- density functional theory
- patient reported outcomes
- molecular dynamics