Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19.
Payam TabarsiSomayeh SharifyniaMihan Pourabdollah ToutkaboniZahra AbtahianMohammad RahdarArefeh Sadat MirahmadianAtousa HakamifardPublished in: Case reports in medicine (2022)
Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal etiology of Aspergillus flavus and Rhizopus arrhizus in case 1 and Aspergillus fumigatus and Rhizopus arrhizus in case 2. Both patients received liposomal amphotericin B then posaconazole combined with aggressive surgical debridement of necrotic tissues with a favorable clinical outcome. Mixed etiology AIFR can influence the outcome; hence, further studies are required upon this new threat.
Keyphrases
- coronavirus disease
- end stage renal disease
- sars cov
- ejection fraction
- newly diagnosed
- chronic kidney disease
- liver failure
- peritoneal dialysis
- prognostic factors
- respiratory failure
- gene expression
- emergency department
- coronary artery disease
- cardiovascular disease
- intensive care unit
- drug induced
- patient reported outcomes
- aortic dissection