Combining tissue and circulating tumor DNA increases the detection rate of a CTNNB1 mutation in hepatocellular carcinoma.
Stine Karlsen OversoeMichelle Simone ClementBritta WeberHenning GrønbækStephen Jacques Hamilton-DutoitBoe Sandahl SorensenJens KelsenPublished in: BMC cancer (2021)
Combining analysis of ctDNA and tumor tissue increased the detection rate of CTNNB1 mutation in HCC patients. A liquid biopsy approach may be useful in a tailored therapy of HCC.