Clinical utility of hereditary cancer panel testing: Impact of PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D results on patient management and adherence to provider recommendations.
Valentina VysotskaiaK Eerik KaseniitLeslie BucheitKaylene ReadyKristin PriceKatherine Johansen TaberPublished in: Cancer (2019)
Testing for PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D changed management for those carrying PVs. Provider recommendations were aligned with guidelines, and patients adhered to recommendations, both of which are critical for reducing both long-term cancer morbidity and mortality.
Keyphrases
- dna repair
- dna damage
- clinical practice
- papillary thyroid
- end stage renal disease
- primary care
- dna damage response
- squamous cell
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- lymph node metastasis
- type diabetes
- squamous cell carcinoma
- childhood cancer
- case report
- young adults
- metabolic syndrome
- glycemic control