A Prospective Double-Blinded Comparison of Reflectance Confocal Microscopy with Conventional Histopathology for In Vivo Assessment in Oral Cancer.
Daniella K ZanoniPaula Demétrio De Souza FrançaCristina ValeroGary PetersonMarco ArdigòRonald A GhosseinStephen W DuszaDanielli MatsuuraDaniel W ScholfieldDauren AdilbayPablo H MonteroJocelyn MigliacciNaga Vara Kishore PillarsettyKivanc KoseIan GanlyMilind RajadhyakshaSnehal G PatelPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
RCM imaging is a promising technology for non-invasive in vivo diagnosis of OSCC and for real-time intraoperative evaluation of mucosal surgical margins. Its inherent constraint, however, stems from the diminished capability to evaluate structures located at more substantial depths within the tissue.