A Tracheal Aspirate-Derived Airway Basal Cell Model Reveals a Proinflammatory Epithelial Defect in Congenital Diaphragmatic Hernia.

Richard WagnerGaurang M AmonkarWei WangJessica E ShuiKamakshi BankotiWai Hei TseFrances A HighJill M ZalieckasTerry L BuchmillerAugusto ZaniRichard KeijzerPatricia K DonahoePaul Hubert LerouXingbin Ai

Published in: American journal of respiratory and critical care medicine (2023)

Our findings have identified an underlying proinflammatory signature and BSC differentiation defects as a potential therapeutic target for airway epithelial defects in CDH.

Keyphrases

single cell
cell therapy
stem cells
human health
risk assessment
mesenchymal stem cells