Neutrophil extracellular traps induce intrahepatic thrombotic tendency and liver damage in cholestatic liver disease.

Muxin YuXiaowen LiLong XuChuwei ZhengWeiwei PanHui ChenXiaoyu LiuXianshan ZhangJinming Zhang

Published in: Hepatology communications (2024)

NETs promote intrahepatic activation of coagulation and inflammation, leading to liver tissue injury. Strategies targeting NET formation may offer a potential therapeutic approach for treating cholestatic liver disease.

Keyphrases

liver injury
oxidative stress
liver fibrosis
drug induced
drug delivery