A haplotype of three SNPs in FTO had a strong association with body composition and BMI in Iranian male adolescents.
Naser KalantariNastaran Keshavarz MohammadiPantea IzadiSaeid DoaeiMaryam GholamalizadehHassan Eini-ZinabTuire SalonurmiShahram RafieifarReza JanipoorGhasem Azizi TabeshPublished in: PloS one (2018)
A haplotype in the first intron of the FTO gene had a strong association with obesity indices in Iranian adolescent males. The FTO gene polymorphisms might have greater effects on anthropometric indices than what was previously imagined. Moreover, we suggested that the FTO gene exerted their effects on anthropometric measurements through haplotypes (and not single SNPs).
Keyphrases
- body composition
- genome wide
- young adults
- resistance training
- bone mineral density
- copy number
- metabolic syndrome
- insulin resistance
- type diabetes
- weight gain
- mental health
- dna methylation
- body mass index
- genome wide identification
- weight loss
- postmenopausal women
- high intensity
- genome wide association
- high fat diet induced
- genome wide analysis
- gene expression