A phase I and extension study of S-1 and carboplatin for previously untreated patients aged 75 years or more with advanced non-small cell lung cancer -TCOG 1101.
Takashi KasaiKiyoshi MoriKazuma KishiTakayuki KaburagiYukio HosomiHisao ImaiYutaka YamadaMakiko YomotaSyuhei MoriguchiMasahiro SeikeKoichi MinatoAkihiko Gemmanull nullPublished in: International journal of clinical oncology (2020)
The recommended doses for this combination therapy are carboplatin AUC 5 and S-1 80 mg/m2/day every 3 weeks, and this combination is effective with tolerable toxicities for advanced NSCLC patients ≥ 75 years old.