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Characterisation of the Leishmania donovani/L. infantum Hybrid Isolated from an Autochothonous Kala-Azar Patient: Preliminary Results of an In Vivo Model

Ozgur KurtNesteren Mansur ÖzenElif Merve AydınDeniz Ece KayaCavit Kerem KayhanSinem Öktem OkulluÜmit İnceFadile Yıldız Zeyrek
Published in: Turkiye parazitolojii dergisi (2021)
The obtained results show that hybrid Leishmania and reference L. donovani and L. infantum strains reached the liver and spleens of Balb/C mice in SGs but were of no pathological consequence. Yet, these three Leishmania isolates caused skin lesions when applied subcutaneously in Balb/C mice in another study. The findings presented in this study will be reassessed upon completion of the project, once the final results are obtained.
Keyphrases
  • high fat diet induced
  • metabolic syndrome
  • skeletal muscle