Fermitin family homolog-2 (FERMT2) is highly expressed in human placental villi and modulates trophoblast invasion.

Eiko KawamuraGina B HamiltonEwa I MiskiewiczDaniel J MacPhee

Published in: BMC developmental biology (2018)

The detection of FERMT2 throughout extravillous trophoblast columns and the results of invasion assays demonstrated that this protein is likely an important regulator of integrin activation in extravillous cells to modulate migration and invasion.

Keyphrases

cell migration
induced apoptosis
endothelial cells
cell cycle arrest
induced pluripotent stem cells
high throughput
endoplasmic reticulum stress
liquid chromatography
loop mediated isothermal amplification
cell death
protein protein
signaling pathway
real time pcr
oxidative stress
binding protein
small molecule