Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization.

Meng-Tong XueWen-Jie ShengXue SongYu-Jiao ShiZhi-Jun GengLin ShenRui WangHe-Zuo LüJian-Guo Hu

Published in: CNS neuroscience & therapeutics (2022)

This study reveals a novel effect of ATL-III in the regulation of microglial/macrophage polarization and provides initial evidence that ATL-III has potential therapeutic benefits in SCI rats.

Keyphrases

spinal cord
neuropathic pain
spinal cord injury
inflammatory response
lipopolysaccharide induced
lps induced
signaling pathway