Synthesis and Properties of 5-Azaullazines.

Sophie JankeSebastian BoldtPascal NakielskiAlexander Villinger Peter Ehlers Peter Langer

Published in: The Journal of organic chemistry (2023)

5-Azaullazines, indolizino[6,5,4,3- ija ][1,5]naphthyridines, and their benzo-fused analogues were prepared in three steps by combination of Pd catalyzed cross-coupling reactions with Brønsted acid mediated cycloisomerisations. The reaction tolerates various substitution patterns and functional groups and proceeds in high yields. Optical and electrochemical properties of selected products were studied experimentally and by DFT calculations.

Keyphrases

density functional theory
molecular docking
gold nanoparticles
molecular dynamics simulations
molecular dynamics
high resolution
ionic liquid
room temperature
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molecularly imprinted
solid state