Alterations of Hemostatic Molecular Markers During Acute Large Vessel Occlusion Stroke.

Xin XuYiming SongWenbo Cao Xuesong BaiXinyu WangPeng GaoJian ChenYanfei ChenBin YangYabing WangFei ChenQingfeng MaBo YuLingyun Jia

Published in: Journal of the American Heart Association (2024)

We observed a hyperactive state of the coagulation-fibrinolysis system within the local ischemic region during hyperacute stroke. Rapid automated measurement of hemostatic molecular markers, particularly TAT, PIC, and sTM, during intra-arterial procedures may provide additional information for stroke risk stratification and therapeutic decision-making, and warrants further investigation.

Keyphrases

atrial fibrillation
decision making
cerebral ischemia
liver failure
machine learning
deep learning
single molecule
high throughput
healthcare
subarachnoid hemorrhage
ischemia reperfusion injury
drug induced
brain injury
blood brain barrier
single cell
aortic dissection
loop mediated isothermal amplification