A self-adjuvanting anti-tumor nanoliposomal vaccine based on fluorine-substituted MUC1 glycopeptide.
Peijie DongSuying ChengYudie WangHang GaoYongmin ZhangTao ZhuPeng YuXin MengPublished in: Chemical communications (Cambridge, England) (2022)
Herein, a self-adjuvanting fluorinated MUC1-based nanoliposomal antitumor vaccine was constructed for the first time. Both the tumor-associated antigen and the mode of its presentation affect the immune response for antitumor vaccines.