Bioavailability and cardiovascular effects of adrenaline administered by Anapen 500 μg auto-injector in healthy volunteers.
Thierry DuvauchellePhilippe RobertYves DonazzoloSabrina LoyauBernard OrlandiniPhilippe LehertJeanne-Marie LecomteJean-Charles SchwartzPublished in: British journal of clinical pharmacology (2022)
A 500 μg adrenaline injection via Anapen produced rapid PK/PD changes in normal weight, overweight and obese subjects, irrespective of intramuscular or subcutaneous injection, and was well tolerated.