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Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386.

Rebecca E McHughJohn T MunnochAndrew J RoePaul A Hoskisson
Published in: Access microbiology (2022)
We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.
Keyphrases
  • genome wide
  • escherichia coli
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • copy number
  • gene expression
  • biofilm formation
  • single cell
  • cystic fibrosis
  • antimicrobial resistance
  • amino acid
  • genome wide identification