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Multiomics and Machine Learning Accurately Predict Clinical Response to Adalimumab and Etanercept Therapy in Patients With Rheumatoid Arthritis.

Weiyang TaoArno N ConcepcionMarieke VianenAnne C A MarijnissenFloris P G J LafeberTimothy R D J RadstakeAridaman Pandit
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Our findings indicate that machine learning models based on molecular signatures accurately predict response before ADA and ETN treatment, paving the path toward personalized anti-TNF treatment.
Keyphrases
  • machine learning
  • rheumatoid arthritis
  • artificial intelligence
  • ankylosing spondylitis
  • deep learning
  • combination therapy
  • smoking cessation
  • cell therapy