Liposomal chrysin attenuates hepatic ischaemia-reperfusion injury: possible mechanism via inhibiting NLRP3 inflammasome.

Rui HuangZizuo ZhaoXujie JiangWeiwei LiLidan ZhangBin WangHong-Tao Tie

Published in: The Journal of pharmacy and pharmacology (2021)

LC has good biocompatibility, and it could attenuate HIR-induced injury. Its mechanism was associated with NLRP3 inflammasome inhibition, and LC might be an effective drug for treating and preventing HIR-induced injury.

Keyphrases

nlrp inflammasome
high glucose
diabetic rats
drug induced
mass spectrometry
simultaneous determination
acute myocardial infarction
signaling pathway
oxidative stress
endothelial cells
blood brain barrier
heart failure
acute coronary syndrome
cerebral ischemia
brain injury
high resolution mass spectrometry