A Phase 1b/2 Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma.
Andrew L CovelerMatthew J ReilleyMark M ZalupskiTeresa MacarullaChristos FountzilasMariano Ponz-SarviséAdnan NagrialNataliya V UbohaSophia FrentzasMichael James OvermanAnne M NoonanWells A MessersmithNick PavlakisNiharika B MettuIna BishaYing WangPaul SmithElina MurtomakiAgata A BielskaVeronique BragulatZachary A CooperRakesh KumarDavid R SpigelPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Although the safety profile was acceptable, this study did not meet its primary efficacy endpoint.