IL17A Depletion Affects the Metabolism of Macrophages Treated with Gemcitabine.
Cecilia RouxGianluca MuccioloJoanna KopeckaFrancesco NovelliChiara RigantiPaola CappelloPublished in: Antioxidants (Basel, Switzerland) (2021)
Overall, we provide a proof-of-concept that combining an anti-IL17A antibody with gemcitabine may represent an effective strategy to modulate macrophages and enhance the anti-tumor response, especially in pancreatic cancer where gemcitabine is widely used.
Keyphrases