Efficacy of Vinflunine for Patients with Metastatic Urothelial Cancer after Immune Checkpoint Inhibitor Pretreatment-A Retrospective Multicenter Analysis.
Felix RiedelMara MünkerFlorian RoghmannJohannes BreyerMarco J SchnabelMaximilian BurgerDanijel SikicThomas BüttnerManuel RitterKiriaki HillerFelix WezelChristian BolenzFriedemann ZengerlingPublished in: Cancers (2022)
This analysis supports the sequential use of vinflunine in post-ICI patients since the vinca-alkaloid retains a measurable clinical activity in these heavily pretreated patients. The therapeutic benefit may be higher than demonstrated in previous studies.