Anti-Valosin-Containing Protein (VCP/p97) Autoantibodies in Inclusion Body Myositis and Other Inflammatory Myopathies.

Adam Amlani May Yee ChoiKatherine A BuhlerMarie HudsonMark TarnopolskyLauren BradyHeinrike SchmelingMark G SwainCory StinglAnn M Reed Marvin J Fritzler

Published in: ACR open rheumatology (2022)

Anti-VCP has low sensitivity and moderate specificity for sIBM but may help fill the seronegative gap in sIBM. Further studies are needed to determine whether anti-VCP is a biomarker for a clinical phenotype that may have clinical value.

Keyphrases

systemic lupus erythematosus
rheumatoid arthritis
high intensity
interstitial lung disease
systemic sclerosis
binding protein
idiopathic pulmonary fibrosis
case control