Gene-based analysis of ADHD using PASCAL: a biological insight into the novel associated genes.

Aitana Alonso-GonzalezManuel CalazaCristina Rodriguez-FontenlaAngel Carracedo

Published in: BMC medical genomics (2019)

PASCAL has been revealed as an efficient tool to extract additional information from previous GWAS using their summary statistics. This study has identified novel ADHD associated genes that were not previously reported when other GBA methods were employed. Moreover, a biological insight into the biological function of the ADHD associated genes across brain regions and neurodevelopmental stages is provided.

Keyphrases

attention deficit hyperactivity disorder
genome wide
genome wide identification
autism spectrum disorder
working memory
bioinformatics analysis
genome wide analysis
dna methylation
white matter
multiple sclerosis
single cell
health information
anti inflammatory