Methamphetamine-induced changes in myocardial gene transcription are sex-dependent.

Hasitha ChavvaDaniel A BrazeauJames DenvirDonald A PrimeranoJun FanSarah L SeeleyBoyd R Rorabaugh

Published in: BMC genomics (2021)

These data demonstrate that female rats are more sensitive than males to methamphetamine-induced changes in the myocardial transcriptome and that methamphetamine does not induce changes in myocardial transcription that persist long term after exposure to the drug has been discontinued.

Keyphrases

left ventricular
transcription factor
gene expression
rna seq
single cell
copy number
emergency department
heart failure
big data
machine learning
drug induced
data analysis