Plasmacytoid Dendritic Cells in Patients with MGUS and Multiple Myeloma.

Andrea Knight Lucie ŘíhováRomana KralovaMiroslav PenkaZdenek AdamLudek PourMartin PiskacekRoman Hájek

Published in: Journal of clinical medicine (2021)

Our results show altered pDC frequencies in the BM microenvironment in MGUS and MM patients at diagnosis. We showed the tumor-promoting function of pDCs that may mediate immune deficiencies affecting long-term disease control and treatment outcome.

Keyphrases

dendritic cells
end stage renal disease
immune response
regulatory t cells
multiple myeloma
ejection fraction
newly diagnosed
stem cells
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes