Hyperpolarized Metabolic Imaging Detects Latent Hepatocellular Carcinoma Domains Surviving Locoregional Therapy.
Nicholas R PerkonsRyan M KieferMichael C NojiMehrdad PourfathiDaniel AckermanSarmad SiddiquiDavid TischfieldEnri ProfkaOmar JohnsonStephen PickupAnthony MancusoAustin PantelMichelle R DenburgGregory J NadolskiStephen J HuntEmma E FurthStephen KadlecekTerence P F GadePublished in: Hepatology (Baltimore, Md.) (2020)
These studies provide a paradigm for imaging latent, treatment-refractory cancer cells, suggesting that DNP-MRSI provides a technology for this application.