Testing the structural disconnection hypothesis: Myelin content correlates with memory in healthy aging.
Andrea Mendez ColmenaresMichael L ThomasCharles AndersonDavid B ArciniegasVince CalhounIn-Young ChoiArthur F KramerKaigang LiJongho LeePhil LeeAgnieszka Z BurzynskaPublished in: Neurobiology of aging (2024)
Our findings support the disconnection hypothesis, showing that myelin decline contributes to age-related memory loss and opens avenues for interventions targeting myelin health.