E3 ubiquitin ligase MAGI3 degrades c-Myc and acts as a predictor for chemotherapy response in colorectal cancer.

Haibo WangWenjing YangQiong QinXiaomei YangYing YangHua LiuWenxiu LuSiyu GuXuedi CaoDuiping FengZhongtao ZhangJunqi He

Published in: Molecular cancer (2022)

MAGI3 is a novel E3 ubiquitin ligase by degradation of c-Myc to regulate CRC development and may act as a potential predictor of adjuvant chemotherapy for CRC patients.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
risk assessment
patient reported outcomes
locally advanced
human health
rectal cancer