Repeated Glutathione Sodium Salt Infusion May Counteract Contrast-Associated Acute Kidney Injury Occurrence in ST-Elevation Myocardial Infarction Patients Undergoing Primary PCI: A Randomized Subgroup Analysis of the GSH 2014 Trial.
Alessio ArriviGiacomo PucciMartina SordiMarcello DominiciFrancesco BarillàRoberto CarnevaleAmalia MorgantiniRiccardo RosatiEnrico MangieriGaetano TanzilliPublished in: Life (Basel, Switzerland) (2023)
the results of this sub-study, which show a significant trend towards an improved nephroprotection in the experimental group, led to the hypothesis of a possible new prophylactic approach to counteract CA-AKI using repeated GSS infusion. Subsequent studies with specific clinical outcomes would be necessary to confirm these data.
Keyphrases
- st elevation myocardial infarction
- acute kidney injury
- percutaneous coronary intervention
- patients undergoing
- cardiac surgery
- low dose
- phase iii
- acute myocardial infarction
- coronary artery disease
- st segment elevation myocardial infarction
- acute coronary syndrome
- risk assessment
- magnetic resonance
- antiplatelet therapy
- clinical trial
- study protocol
- coronary artery bypass grafting
- magnetic resonance imaging
- contrast enhanced
- computed tomography
- fluorescent probe
- data analysis
- artificial intelligence
- light emitting
- double blind