Preterm prelabour rupture of membranes before 23 weeks' gestation: prospective observational study.
Laura GoodfellowAngharad CareCiara CurranDevender RobertsMark A TurnerMarian KnightAlfirevic ZarkoPublished in: BMJ medicine (2024)
In this study, 26% of women who had very early PPROM with expectant management had babies that survived to discharge from hospital. Morbidity and mortality rates were high for both mothers and neonates. Maternal sepsis is a considerable risk that needs more research. These data should be used in counselling families with PPROM before 23 weeks' gestation, and currently available guidelines should be updated accordingly.
Keyphrases
- gestational age
- birth weight
- preterm birth
- low birth weight
- preterm infants
- polycystic ovary syndrome
- healthcare
- acute kidney injury
- electronic health record
- intensive care unit
- big data
- clinical practice
- body mass index
- septic shock
- type diabetes
- acute care
- machine learning
- physical activity
- adverse drug
- pregnant women
- hepatitis c virus
- skeletal muscle