Population Pharmacokinetic Modeling of Abacavir/Dolutegravir/Lamivudine to Support a Fixed-Dose Combination in Children with HIV-1.

Hardik ChandasanaSven C van DijkmanRashmi MehtaMark BushHelena RabiePatricia FlynnTim R CresseyEdward P AcostaKristina M Brooksnull null

Published in: Infectious diseases and therapy (2024)

This model-based approach leveraged existing pediatric data and models to confirm dosing of ABC/DTG/3TC FDC formulations in children with HIV-1. This analysis supports ABC/DTG/3TC FDC dosing in children weighing ≥ 6 kg.

Keyphrases

antiretroviral therapy
young adults
hiv positive
hiv infected
human immunodeficiency virus
hepatitis c virus
hiv testing
hiv infected patients
hiv aids
men who have sex with men
big data