Exploring molecular pathology of chronic kidney disease in systemic sclerosis by analysis of urinary and serum proteins.

Edward P SternRobert UnwinAine BurnsVoon H Ong Christopher P Denton

Published in: Rheumatology advances in practice (2021)

Urinary levels of candidate molecular markers appear to reflect SSc-CKD more than serum markers. MCP1 and ICAM-1 are promising molecular markers for SSc-CKD and might be potential biomarkers of SSc renal involvement. This might be explored in future prospective analyses.

Keyphrases

chronic kidney disease
systemic sclerosis
end stage renal disease
interstitial lung disease
single molecule
peritoneal dialysis