The controversy of drug hypersensitivity in patients with cystic fibrosis and review of the literature.
Gokcen Dilsa TugcuNagehan EmiraliogluEbru YalcinUmit Murat SahinerDeniz DogruBulent Enis SekerelUgur OzcelikNural KiperOzge SoyerPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2022)
Actual drug hypersensitivity was demonstrated in 2 of 219 patients (0.9%) with non-beta-lactam antibiotics. These results conflict with previous researches that showed higher drug hypersensitivity rates but are consistent with some recent studies. Allergological diagnostic workup is mandatory in patients with cystic fibrosis in case of a suspicious DHR.