Body weight and blood pressure changes on dolutegravir-, efavirenz- or atazanavir-based antiretroviral therapy in Zimbabwe: a longitudinal study.
Tinei ShamuMatthias EggerTinashe MudzvitiCleophas ChimbeteteJusten ManasaNanina AndereggPublished in: Journal of the International AIDS Society (2024)
Among PLHIV starting ART or switching to a new regimen, DTG-based ART was associated with larger weight gains and a substantial increase in the prevalence of high blood pressure. Routine weight and blood pressure measurement and interventions to lower blood pressure could benefit PLHIV on DTG-based ART. Further studies are needed to elucidate the mechanisms and reversibility of these changes after discontinuation of DTG.
Keyphrases
- blood pressure
- antiretroviral therapy
- hiv infected
- body weight
- hiv infected patients
- hypertensive patients
- human immunodeficiency virus
- hiv positive
- heart rate
- hiv aids
- physical activity
- body mass index
- weight loss
- weight gain
- metabolic syndrome
- blood glucose
- risk factors
- hepatitis c virus
- skeletal muscle
- case control