Clinical Characteristics and Severity of COVID-19 Disease in Patients from Boston Area Hospitals.
Hesamaddin Torabi DashtiDavid BatesJulie M FiskioElise C RocheSamia MoraDemler V OlgaPublished in: medRxiv : the preprint server for health sciences (2020)
We summarize key demographic, clinical, and medical characteristics of patients with respect to the severity of COVID-19 disease using Electronic Health Records Data of 4,140 SARS-CoV-2 positive subjects from several large Boston Area Hospitals. We found that prior use of antihypertensive medications as well as lipid lowering and other cardiovascular drugs (such as direct oral anticoagulants and antiplatelets) all track with increased severity of COVID-19 and should be further investigated with appropriate adjustment for confounders such as age and frailty. The three most common prior comorbidities are hyperlipidemia, hypertension, and prior pneumonia, all associated with increased severity.
Keyphrases
- sars cov
- electronic health record
- coronavirus disease
- direct oral anticoagulants
- respiratory syndrome coronavirus
- blood pressure
- healthcare
- end stage renal disease
- venous thromboembolism
- newly diagnosed
- prognostic factors
- atrial fibrillation
- high fat diet
- big data
- adverse drug
- patient reported outcomes
- high resolution
- artificial intelligence
- atomic force microscopy
- single molecule
- patient reported